The 635-mile road trip from San Francisco to Portland will take 10 hours to drive before taking stops into account. Longer routes along the Pacific Coast Highway or the Sierra Nevada and the Cascades are 900 and 820 miles long taking 17 to 18 hours. Keep reading to learn all about the best routes, places to stop and things to see along the way.The total driving time is 10 hours, 14 minutes. Your trip begins at Portland International Airport in Portland, Oregon. It ends at San Francisco International Airport in San Francisco, California. If you're planning a road trip, you might be interested in seeing the total driving distance from PDX to SFO. You can also calculate the cost to ...12:24. Lufthansa / Operated by United Airlines 1823. «. ←. 1. 2. →. ». (PDX to SFO) Track the current status of flights departing from (PDX) Portland International Airport and arriving in (SFO) San Francisco International Airport.Find cheap flights from Portland to San Francisco Bay Area from $29. Round-trip. 1 adult. Economy. 0 bags. Direct flights only Add hotel. sáb. 5/11. sáb. 5/18. Search hundreds of …Wed, May 1 SFO – PDX with Frontier Airlines. Direct. from C$72. San Francisco.C$72 per passenger.Departing Wed, Apr 17, returning Sat, Apr 20.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from Portland on Wed, Apr 17, arriving in San Francisco International.Inbound direct flight with Frontier ...Portland, OR to New York (LaGuardia), NY. departing on 11/5. one-way starting at*. $209. Book now. * Restrictions and exclusions apply. Seats and dates are limited. Select markets. 18 travel days available.Direct flights from Portland to San Francisco. All flights from PDX to SFO non-stop. There are direct flights from Portland International, Oregon, USA to San Francisco International (SFO), California, USA every day of the week with Alaska Airlines, United Airlines and Frontier Airlines.The flight distance is 553 miles and the trip usually takes about 1 hour …Amazing Delta PDX to SFO Flight Deals. The cheapest flights to San Francisco Intl. found within the past 7 days were $102 round trip and one way. Prices and availability subject to change. Additional terms may apply. Tue, May 14 - Wed, May 15.Get Delta cheap flights from Portland to San Francisco. Book one-way or return flight from PDX → SFO with Delta (DL) deals & save!You can visit San Francisco or nearby cities when you fly to California on United. Find your vacation package to San Francisco with United Vacations. Book cheap flights to San Francisco (SFO) with United …In the last 72 hours, the best return deals on flights connecting Portland to San Francisco were found on Frontier ($38) and Delta ($157). Frontier proposed the cheapest one-way …What is the average airfare San Francisco to Portland? Average Airfare to Portland from San Francisco can range from $53 to $4963. Early bookings can usually assist you in getting the cheapest flight tickets. Booking in advance is one of the most proven ways to obtain discount airfares.Tue, 14 May SFO - PDX with Frontier Airlines. Direct. from £39. San Francisco. £46 per passenger.Departing Sat, 1 Jun, returning Wed, 5 Jun.Return flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departs from Portland on Sat, 1 Jun, arriving in San Francisco International.Inbound direct flight with Frontier Airlines ...$60 Cheap Alaska Airlines flights Portland (PDX) to San Francisco (SFO) Prices were available within the past 7 days and start at $60 for one-way flights and $108 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.Wed, May 1 SFO – PDX with Frontier Airlines. Direct. from C$72. San Francisco.C$72 per passenger.Departing Wed, Apr 17, returning Sat, Apr 20.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from Portland on Wed, Apr 17, arriving in San Francisco International.Inbound direct flight with Frontier ... Flights from Portland (PDX) to San Francisco (SFO) Origin airport. Portland Intl. Destination airport. San Francisco Intl. Airlines serving. Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, JetBlue Airways, Sun Country Airlines, United. Popular airline. Alaska Airlines, Inc., Frontier Airlines and two other airlines fly from San Francisco Airport (SFO) to Portland hourly. Alternatively, you can take a bus from San Francisco Airport (SFO) to Portland via Main St & Market St, Embarcadero, West Oakland, Oakland, and Sacramento Bus Station in around 17h 3m. Airlines.There are 3 airlines that fly direct from San Francisco to Portland. They are: Alaska Airlines, Frontier and United Airlines. The cheapest price of all airlines flying this route was found with Alaska Airlines at $118 for a one-way flight. On average, the best prices for this route can be found at Alaska Airlines.Flights from Portland (PDX) to San Francisco (SFO) Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, JetBlue Airways, Sun Country Airlines, United.Alaska Airlines flights from Portland to San Francisco (PDX - SFO) PDX — SFO. mar 25 — apr 1 1 Searching for cheap flights from Portland to San Francisco? Enjoy comfort, premium cabin legroom and free movies with Alaska Airlines. Find the lowest fares today. Wed, May 29 PDX – SFO with Frontier Airlines. Direct. from $43. Portland.$50 per passenger.Departing Tue, Jun 11, returning Tue, Jun 18.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from San Francisco International on Tue, Jun 11, arriving in Portland.Inbound direct flight with …$78 Cheap Delta flights San Francisco (SFO) to Portland (PDX) Prices were available within the past 7 days and start at $78 for one-way flights and $156 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.The bus journey time between Portland Airport (PDX) and San Francisco International Airport is around 18h 58m and covers a distance of around 715 miles. This includes an average layover time of around 2h 18m. Operated by Pacific Crest Buslines Bend, Flixbus USA, Greyhound USA and others, the Portland Airport (PDX) to San Francisco …Amazing Alaska Airlines SFO to PDX Flight Deals. The cheapest flights to Portland Intl. found within the past 7 days were $113 round trip and $60 one way. Prices and availability subject to change. Additional terms may apply. Tue, Jun 11 - Tue, Jun 11.Fly more and save even more when you travel to San Francisco, CA (SFO) with Frontier where you always find low fares done right. Skip to content-Skip to footer. ... From Portland, OR (PDX) To San Francisco, CA (SFO) One-way / Economy: Departing May 22, 2024: From. $19* Last seen: 56 mins ago. From Ontario/LA, CA (ONT) To San Francisco, CA …Portland. United States. PDX. Portland International Airport. San Francisco. United States. SFO. San Francisco International Airport. Check Prices. Flight schedule. su. mo. tu. we. … Cheap Flights from PDX to SFO starting at $29 One Way, $58 Round Trip. Prices starting at $58 for return flights and $29 for one-way flights to San Francisco Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply. Sat, May 11 - Tue, May 14. Portland to San Francisco Flights. There are 95 flights from Portland (PDX) to San Francisco (SFO) airport operated by 6 airlines. Below you can see the 30 most recent flights from … The best one-way flight to San Francisco from Portland in the past 72 hours is $19. The best round-trip flight deal from Portland to San Francisco found on momondo in the last 72 hours is $38. The fastest flight from Portland to San Francisco takes 1h 47m. Direct flights go from Portland to San Francisco every day. Amazing Alaska Airlines SFO to PDX Flight Deals. The cheapest flights to Portland Intl. found within the past 7 days were $113 round trip and $60 one way. Prices and availability subject to change. Additional terms may apply. Tue, Jun 11 - Tue, Jun 11. Searching for cheap flights from Portland to San Francisco? Enjoy comfort, premium cabin legroom and free movies with Alaska Airlines. Find the lowest fares today. Amazing SFO to PDX Flight Deals. The cheapest flights to Portland Intl. found within the past 7 days were $43 round trip and $29 one way. Prices and availability subject to change. Here are some of the best deals found on KAYAK recently from the most popular airlines for round-trip flights from San Francisco to Portland that are departing in the next months. …Amtrak tickets to San Francisco costs between $82 and USD 95.50 each seat. This $82 train leaves at 11:08 from Portland train station at 1301 W 11th St, Union Station, Sunset Transit Center/TriMet Station. On the contrary, the train leaving at 11:20 have the most expensive ticket to San Francisco for about USD 95.50.23 Best Stops on Your Portland to San Francisco Road Trip. The list is structured below for the best coastal route stops #1-14; and the best mountain route stops are #15-23. Point Reyes in Marin County on the Pacific coast. Dramatic rock formations and coastline viewpoints of Cannon Beach.Alaska Airlines, Inc., Frontier Airlines and two other airlines fly from San Francisco Airport (SFO) to Portland hourly. Alternatively, you can take a bus from San Francisco Airport (SFO) to Portland via Main St & Market St, Embarcadero, West Oakland, Oakland, and Sacramento Bus Station in around 17h 3m. Airlines.Day 1: SF to Mount Shasta. Okay, so technically this itinerary is for 6.25 days. And by that I mean, you need to either get out of the city of San Francisco the evening before or get up super early and get out of the city before traffic hits.Frontier Airlines said Tuesday it will add nonstop flights from PDX to San Francisco, Dallas-Fort Worth and Ontario, California. ... Introductory one-way fares for the new routes start at $19 to ...Wed, May 1 SFO – PDX with Frontier Airlines. Direct. from C$72. San Francisco.C$72 per passenger.Departing Wed, Apr 17, returning Sat, Apr 20.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from Portland on Wed, Apr 17, arriving in San Francisco International.Inbound direct flight with Frontier ...Alaska Airlines, Inc., Frontier Airlines and two other airlines fly from San Francisco Airport (SFO) to Portland hourly. Alternatively, you can take a bus from San Francisco Airport (SFO) to Portland via Main St & Market St, Embarcadero, West Oakland, Oakland, and Sacramento Bus Station in around 17h 3m. Airlines.San Francisco Botanical Garden. The San Francisco Botanical Garden in San Francisco's Golden Gate Park is home to over 50000 individual plants across more than 8000 taxa collected from around the world. Some popular plants here are kept in sections earmarked as Mediterranean, Mild-temperate and Montane tropic.San Francisco - Portland flight deals. Compare flight prices from San Francisco to Portland and find your low cost flight. With Jetcost you will find cheap flights and low cost flights from San Francisco to Portland in one click: just choose the dates of your flight to compare the price of flights from San Francisco to Portland of the major airlines and …Leaves PDX Portland 3 minutes early. 14 minutes taxiing out. 1 hour, 24 minutes in the air. 5 minutes taxiing in. Arrives SFO San Francisco 5 minutes early. FlightSphere. ... (PDX) to San Francisco (SFO). Keep in mind that Southwest may fly to other nearby airports, as they will often fly into smaller airpors instead of larger ones. ...Find and book cheap flights from PDX to SFO with Expedia. Compare prices, dates, airlines and deals for roundtrip or one-way flights.Cheap Flights from SFO to PDX starting at $29 One Way, $58 Round Trip. Prices starting at $58 for return flights and $29 for one-way flights to Portland Intl. were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply. Sat, May 4 - Tue, May 7.Apr 29, 2024 · Tour San Francisco City Hall, a Beaux-Arts beauty, and make sure to look up - the dome is a replica of St. Peter's Basilica in Rome. Compare cheap flights to San Francisco with Alaska Airlines. Enjoy our low prices and generous experience. Book the lowest fares on San Francisco flights today. Compare cheap flights to San Francisco with Alaska Airlines. Enjoy our low prices and generous experience. Book the lowest fares on San Francisco flights today. ... Portland (PDX) to. San Francisco (SFO) Depart: May 22, 2024. From. $60* Seen: 14 hours ago. One-way | Saver. Book now. New York (JFK) to. San Francisco (SFO) …Amazing American Airlines PDX to SFO Flight Deals. The cheapest flights to San Francisco Intl. found within the past 7 days were $247 round trip and $115 one way. Prices and availability subject to change. Additional terms may apply.Airfares from $118 One Way, $236 Round Trip from Portland to San Francisco. Prices starting at $236 for return flights and $118 for one-way flights to San Francisco were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply. Fri, Sep 13 - Tue, Sep 24. PWM. Flights from Portland (PDX) to San Francisco (SFO) Origin airport. Portland Intl. Destination airport. San Francisco Intl. Airlines serving. Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, JetBlue Airways, Sun Country Airlines, United. Popular airline. Flights. To United States. Portland, OR - San Francisco, CA. Find cheap fares from Portland, OR (PDX) to San Francisco, CA (SFO) with Frontier Airlines. Enjoy unlimited savings all year with the Discount Den℠! The best one-way flight to San Francisco from Portland in the past 72 hours is $19. The best round-trip flight deal from Portland to San Francisco found on momondo in the last 72 hours is $38. The fastest flight from Portland to San Francisco takes 1h 47m. Direct flights go from Portland to San Francisco every day.Amazing Alaska Airlines PDX to SFO Flight Deals. The cheapest flights to San Francisco Intl. found within the past 7 days were $119 round trip and $60 one way. Prices and availability subject to change. Additional terms may apply. Tue, Apr 16 - Tue, Apr 23. Wed, May 1 SFO – PDX with Frontier Airlines. Direct. from C$72. San Francisco.C$72 per passenger.Departing Wed, Apr 17, returning Sat, Apr 20.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from Portland on Wed, Apr 17, arriving in San Francisco International.Inbound direct flight with Frontier ... Flights from Portland to San Francisco. Use Google Flights to plan your next trip and find cheap one way or round trip flights from Portland to San Francisco.E75L. Arrived / Gate Arrival. Fri 08:00AM PDT. 09:52AM PDT Fri. San Francisco Int'l (KSFO) - Portland Intl (KPDX) - Flight Finder - Find and track any flight (airline or private) -- search by origin and destination.$60 Cheap United flights Portland (PDX) to San Francisco (SFO) Prices were available within the past 7 days and start at $60 for one-way flights and $113 for round trip, for the …San Francisco - Portland flight deals. Compare flight prices from San Francisco to Portland and find your low cost flight. With Jetcost you will find cheap flights and low cost flights from San Francisco to Portland in one click: just choose the dates of your flight to compare the price of flights from San Francisco to Portland of the major airlines and …Wed, May 1 SFO – PDX with Frontier Airlines. Direct. from C$72. San Francisco.C$72 per passenger.Departing Wed, Apr 17, returning Sat, Apr 20.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from Portland on Wed, Apr 17, arriving in San Francisco International.Inbound direct flight with Frontier ...E75L. Arrived / Gate Arrival. Fri 08:00AM PDT. 09:52AM PDT Fri. San Francisco Int'l (KSFO) - Portland Intl (KPDX) - Flight Finder - Find and track any flight (airline or private) -- search by origin and destination.7h 04m SFO-PDX. 4/21 dom. multi-stop United Airlines. 6h 24m PDX-SFO. $898. Search. Show more results. Search by stops Nonstop 1 stop 2+ stops. Search by airline Frontier Spirit Airlines Alaska Airlines American Airlines United Airlines. Search by price $130 or less $150 or less $310 or less $640 or less $900 or less.Amazing Alaska Airlines PDX to SFO Flight Deals. The cheapest flights to San Francisco Intl. found within the past 7 days were $119 round trip and $60 one way. Prices and availability subject to change. Additional terms may apply. Tue, Apr 16 - Tue, Apr 23.The Portland to San Francisco drive (along Highway 1) is iconic and filled with incredible sights and towns. I did this road trip during my last few days on the West Coast, and I’ve pinned some amazing places you must see! This is one of my favorite road trips, as there’s so much variation in landscape and terrain, but its super accessible ...Use Google Flights to explore cheap flights to anywhere. Search destinations and track prices to find and book your next flight.Compare cheap flights to San Francisco with Alaska Airlines. Enjoy our low prices and generous experience. Book the lowest fares on San Francisco flights today. ... Portland (PDX) to. San Francisco (SFO) Depart: May 22, 2024. From. $60* Seen: 14 hours ago. One-way | Saver. Book now. New York (JFK) to. San Francisco (SFO) …Find the departure gate, as well as the departure and arrival times for your Alaska Airlines flight. Amazing SFO to PDX Flight Deals. The cheapest flights to Portland Intl. found within the past 7 days were $43 round trip and $29 one way. Prices and availability subject to change. PDX Customer Service. Staffed Daily from 6 a.m. - 11:30 p.m. Information & FAQs. Call or Text: Call Us 503.460.4234. Text Us. Toll Free: 1.877.739.4636. Lost & Found 503.460.4272. Portland International Airport (PDX) is open 24 hours, 7 days per week. Airline ticket counter and checkpoint hours vary.Portland. United States. PDX. Portland International Airport. San Francisco. United States. SFO. San Francisco International Airport. Check Prices. Flight schedule. su. mo. tu. we. …23 Best Stops on Your Portland to San Francisco Road Trip. The list is structured below for the best coastal route stops #1-14; and the best mountain route stops are #15-23. Point Reyes in Marin County on the Pacific coast. Dramatic rock formations and coastline viewpoints of Cannon Beach.Apr 29, 2024 · Tour San Francisco City Hall, a Beaux-Arts beauty, and make sure to look up - the dome is a replica of St. Peter's Basilica in Rome. Compare cheap flights to San Francisco with Alaska Airlines. Enjoy our low prices and generous experience. Book the lowest fares on San Francisco flights today. Wed, May 22 PDX – SFO with Frontier Airlines. Direct. from $36. Portland.$37 per passenger.Departing Tue, Apr 30, returning Wed, May 1.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from San Francisco International on Tue, Apr 30, arriving in Portland.Inbound direct flight with Frontier ... Return flights from Portland PDX to San Francisco SFO with JetBlue Airways If you’re planning a round trip, booking return flights with JetBlue Airways is usually the most cost-effective option. With airfares ranging from $719 to $719, it’s easy to find a …Portland to Minneapolis Flights. Flights from PDX to MSP are operated 19 times a week, with an average of 3 flights per day. Departure times vary between 00:30 - 23:59. The earliest flight departs at 00:30, the last flight departs at 23:59. However, this depends on the date you are flying so please check with the full flight schedule above to ... Searching for cheap flights from Portland to San Francisco? Enjoy comfort, premium cabin legroom and free movies with Alaska Airlines. Find the lowest fares today. Airfares from $24 One Way, $48 Round Trip from Salem to San Francisco. Prices starting at $48 for return flights and $24 for one-way flights to San Francisco were the cheapest prices found within the past 7 days, for the period specified. Prices and availability are subject to change. Additional terms apply. Sat, May 11 - Tue, May 14.Portland International Airport (PDX) is open 24 hours, 7 days per week. Airline ticket counter and checkpoint hours vary. For airline information, please contact your airline directly - Airlines. Public Records Request. Directions. Portland International Airport 7000 NE Airport Way ...May 17, 2021 · Similarly, if you are driving south, the Portland to San Francisco road trip itinerary takes about 20 hours, considering you begin the trip in Cannon Beach and then follow Highway 101 south to California. If you are looking for a faster road, then consider the I-5. Distance on the Interstate between the two cities is 635 miles and the trip ... The trip from San Francisco to Portland can be as quick as 14 hours 35 minutes and as cost-effective as $72.99. The first bus of the day departs at 6:30 am and the last bus departs at 4:00 pm . Greyhound offers 2 buses daily between San Francisco and Portland. Traveling with Greyhound guarantees free Wifi, access to power sockets, and a ... Searching for cheap flights from Portland to San Francisco? Enjoy comfort, premium cabin legroom and free movies with Alaska Airlines. Find the lowest fares today. Flight Arrivals information at Portland Airport (PDX): Status and Estimated times - Today ... San Francisco (SFO) 09:11 pm UA1359. AC3334. LH8784. NZ9345. TK9589. VA8453. United Airlines. Air Canada . Lufthansa . Air New Zealand . Turkish Airlines . Virgin Australia . E. Conc. E. En Route - On-time [+] Wed, May 22 PDX – SFO with Frontier Airlines. Direct. from $36. Portland.$37 per passenger.Departing Tue, Apr 30, returning Wed, May 1.Round-trip flight with Frontier Airlines.Outbound direct flight with Frontier Airlines departing from San Francisco International on Tue, Apr 30, arriving in Portland.Inbound direct flight with Frontier ... The total driving time is 10 hours, 14 minutes. Your trip begins at San Francisco International Airport in San Francisco, California. It ends at Portland International Airport in Portland, Oregon. If you're planning a road trip, you might be interested in seeing the total driving distance from SFO to PDX. You can also calculate the cost to ...
Amazing Alaska Airlines PDX to SFO Flight Deals. The cheapest flights to San Francisco Intl. found within the past 7 days were $119 round trip and $60 one way. Prices and availability subject to change. Additional terms may apply. Tue, Apr 16 - Tue, Apr 23.. Betvie
The San Francisco International Airport (SFO), located 13 miles from downtown San Francisco, is the airport of choice for people traveling from Portland to San Francisco. In case you need medicine while at the San Francisco International Airport, there is a medical clinic at the International Terminal Main Hall in the Departures Area. Find United Airlines cheap flights from San Francisco to Portland, OR. Enjoy a San Francisco to Portland, OR modern flight experience in premium cabins with Wi-Fi.Plan a trip from SFO to PDX. Use the trip calculator to organize your flight plans or road trip. DRIVING DISTANCE FLYING TIME COST PLACES. From: To: ... (PDX) Book a Flight: SEARCH. Direct Flights: Alaska Airlines United Airlines: Sports Stadiums: Moda Center Providence Park: Book a Vacation: SEARCH. View Map:The Portland to San Francisco drive (along Highway 1) is iconic and filled with incredible sights and towns. I did this road trip during my last few days on the West Coast, and I’ve pinned some amazing places you must see! This is one of my favorite road trips, as there’s so much variation in landscape and terrain, but its super accessible ...Flying time from SFO to PDX. The total flight duration from SFO to PDX is 1 hour, 18 minutes. This is the average in-air flight time (wheels up to wheels down on the runway) based on actual flights taken over the past year. It covers the entire time on a typical commercial flight including take-off and landing.Of the 7,325 flights from Portland International Airport (PDX) to San Francisco International Airport (SFO), 77.61% (5,685 flights) were on time, 6.84% (501 flights) were delayed an average of 15–29 minutes, and 4.41% (323 flights) were delayed an average of 30–44 minutes. Table 2 shows the on-time statistics of the flights from PDX to SFO ...Compare cheap flights to San Francisco with Alaska Airlines. Enjoy our low prices and generous experience. Book the lowest fares on San Francisco flights today. ... Portland (PDX) to. San Francisco (SFO) Depart: May 22, 2024. From. $60* Seen: 14 hours ago. One-way | Saver. Book now. New York (JFK) to. San Francisco (SFO) …Flights from Portland (PDX) to San Francisco (SFO) Origin airport. Portland Intl. Destination airport. San Francisco Intl. Airlines serving. Alaska Airlines, American Airlines, Delta, Frontier Airlines, Hawaiian Airlines, JetBlue Airways, Sun …Route Flight number. Apr 19, 2024. When? United Airlines (UA) Airline. Check status. Check the status of your United Airlines flight by searching by route or flight number. Stay up to date with our flight status tools.PDX -> SFO Portland 48min late Portland (PDX / KPDX) 17 Apr 15:55 PDT: San Francisco 14min late San Francisco (SFO / KSFO) 17 Apr 17:49 PDT: 17 Apr 16:43 48min late 17 Apr 18:03 14min late Show Calendar. CLAIM COMPENSATION Flight delays happen, but that doesn’t mean you have to accept them. You may be ...PDX. Portland , OR. USA. SFO. San Francisco , CA. Distance. 553 miles · (890 km) CHANGE DIRECTION. Flight time. 2 hours and 01 minute. Airlines with direct flights from …Amazing American Airlines PDX to SFO Flight Deals. The cheapest flights to San Francisco Intl. found within the past 7 days were $247 round trip and $115 one way. Prices and availability subject to change. Additional terms may apply.In the last 72 hours, the best return deals on flights connecting Portland to San Francisco were found on Frontier ($38) and Delta ($157). Frontier proposed the cheapest one-way …With a journey time of close to 11 hours, this marathon drive covers quite a distance. In fact, the distance from Portland to San Francisco for the most direct route is roughly 635 miles one way, but that’s not the scenic or exciting way to enjoy a road trip to San Francisco. If you travel along the coast, the distance will be around 750 miles..